糖尿病合并消化性溃疡62例临床分析

目的探讨糖尿病（diabetes mellins,DM）合并消化性溃疡（peptic alcer,PU）与非糖尿病性消化性溃疡的胃镜特点、临床症状、幽门螺杆菌（Hp）感染率及根除率的区别。方法 DM合并PU 62例为观察组;同期非糖尿病性PU 74例为对照组。两组均行胃镜及Hp检查,分析其胃镜特点、Hp感染率、临床症状。Hp阳性者予以常规三联疗法（泮托拉唑40 mg bid,阿莫西林1000 mg bid,克拉霉素500 mg bid）,4周后复查14C-尿素呼气试验,比较两组Hp根除率差异。结果两组胃镜特点、临床症状、Hp感染率及Hp根除率差异均有统计学意义（P〈0.05）。结论 DM合并PU患者临床症状、溃疡发生部位与非糖尿病性消化性溃疡患者均有所区别,对糖尿病患者可常规做胃镜检查,并对Hp感染患者适当延长治疗时间,以提高Hp根除率。

Diabetes mellitus with peptic ulcer:Clinic analysis of 62 cases

Objective To investigate the difference of peptic ulcer(PU) patients with diabetes mellitus(DM) and PU patients without DM in gastroscopic features,clinical symptom,the infection rate and eradication rate of helicobacter pylori(Hp).Methods A total of 136 patients were induced in this study.Sixty-two PU patients with DM were assigned to observation group and 74 PU patients randomly selected in the same period without DM were assigned to control group.All patients underwent gastroscopy and Hp examination.The ...