重症急性胰腺炎继发感染的细菌学研究

目的:研究重症急性胰腺炎继发感染的细菌学特征.方法:对重症胰腺炎伴胰周或腹腔积液的20例患者进行动态血液、腹腔积液细菌培养、鉴定及药物敏感试验.结果:20例中细菌培养阳性的17例,多发生在发病的2～3周(76.5%);感染的细菌以革兰阴性为主;革兰阴性菌感染的患者住院时间明显延长.伴细菌感染者并发症发生率增加且住院时间延长.结论:革兰阴性菌是重症胰腺炎继发感染的主要细菌,多在发病的2～3周出现.PAO2、肠麻痹、APACHE-Ⅱ评分、早期手术可能为影响感染的高危因素.

Bacteriologic Study of Inflammation of Severe Acute Pancreatitis

Objective To investigate the bacteriological features of secondary infection of severe acute pancrcatitis in clinical Methods From October 1999 to March 2001,20 patients admitted with severe acute pancreatitis following peripancreatic or peritoneal fluid collection were treated and observed.Blood and fluid collection were dynamically cultured,and microorganisms cultured were identified,and then drug sensitivity was performed.Results Seventeen of the 20 patients had secondary infection;most infection occurred within 2 and 3 weeks (76.5%) after the onset of acute pancreatitis;gram negative infection was preponderant;the hospital stay was significantly longer in cases of gram negative infected necrosis;cultures in blood were all negative. Conclusion Gram negative bacteria are major microorganisms in infectious complications of severe acute pancreatitis.Most infection occurred within 2 and 3 weeks(76.5%) after the onset of acute pancreatitis.