CT三维重建引导下背根神经节脉冲射频治疗胸背部带状疱疹后神经痛的疗效

目的评价CT引导下背根神经节脉冲射频对带状疱疹后神经痛患者的安全性和疗效。方法带状疱疹后神经痛患者80例，随机分为2组（n=40）：药物组（A组）、脉冲射频加药物组（B组）。根据脊神经节段性分布确定神经痛受累节段，A组在CT三维重建引导下行背根神经节注射复方倍他米松，B组脉冲射频复合复方倍他米松。分别于术前（TO）、术后1d、7d、1个月、3个月（T1～4）进行VAS评分、睡眠干扰评分（SIS）和简化麦吉尔评分（SF-MPQ），并观察并发症的发生情况。结果与术前比较，A组术后T1～2时VAS、SIS和SF-MPQ均降低（P〈0．05），B组术后T1～4时VAS、SIS和SF-MPQ均降低（P〈0．05）；与A组比较，B组T1～4时VAS、SIS和SF-MPQ均降低（P〈O．05）。结论CT三维重建引导下经皮穿刺椎间孔内背根神经节脉冲射频复合复方倍他米松治疗带状疱疹后神经痛效果优于单纯复方倍他米松，且安全性好。

Efficacy of pulsed radiofrequency in the dorsal root ganglia for the treatment of patients with postherpetic neuralgia under the guidance of 3-dimension reconstruction CT

Objective To evaluate the safety and efficacy of pulsed radiofrequency in the dorsal root ganglia for the treatment of patients with postherpetic neuralgia under the guidance of 3-dimen- sion reconstruction CT. Methods Eighty patients suffering from postherpetic neuralgia in thoracic back region were randomly divided into two groups （n=40 each） ： patients in the drug group （group A） were locally injected with compound betamethasone; while in drug plus radiofrequency group （group B） were received pulsed radiofrequency under the guidance of 3-dimension recontruction com- bined with compound betamethasone injection. VAS, sleep interference score （SIS） and a short form of McGill pain questionnaire （SF-MPQ） were used to evaluate the efficacy in pre-operation （TO） and 1 d, 7 d, 1 month, 3 months after the operation（T1-4）. Results Compared with pre-operation, VAS, SIS and SF-MPQ scores were significantly lower at T1-2 in group A and T1-4 in group B （P 〈0.05）. Compared with group A, VAS, SIS and SF-MPQ scores were significantly lower at T1-4 in group B （P〈0.05）. Conclusion Pulsed radiofrequency in the dorsal root ganglia is safe and effec-rive via intervertebral foramen guided by 3-dimension reconstruction CT for the treatment of posther- petic neuralgia.