| 神经生长因子受体P75在脊髓损伤大鼠膀胱和前列腺中的表达 |
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| 引用本文： | 刘浩,邹练,李航旭,张晓毅,张子良. 神经生长因子受体P75在脊髓损伤大鼠膀胱和前列腺中的表达[J]. 辽宁医学院学报, 2012, 33(4): 301-302,385,386 |
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| 作者姓名： | 刘浩 邹练 李航旭 张晓毅 张子良 |
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| 作者单位： | 1. 辽宁医学院,辽宁,锦州,121001
2. 第二炮兵总医院,北京,100088 |
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| 摘 要： | 目的 探讨脊髓损伤大鼠模型膀胱逼尿肌及前列腺神经生长因子受体P75的表达变化及意义.方法 建立脊髓损伤大鼠模型40只,以30只正常大鼠作对照,应用免疫组化方法和图像分析技术,分别检测大鼠膀胱组织及前列腺中P75的变化情况.结果 无论是在膀胱组织还是在前列腺组织P75表达均低于对照组,差异有统计学意义.结论 神经生长因子受体P75的表达降低与脊髓损伤有关.
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| 关 键 词： | 脊髓损伤 P75 膀胱 前列腺 |
The Expression of NGF Receptor P75 in Bladder and Prostate of Rats with Spinal Cord Injury |
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| LIU Hao , ZOU Lian , LI Hangxu , ZHANG Xiaoyi , ZHANG Ziliang. The Expression of NGF Receptor P75 in Bladder and Prostate of Rats with Spinal Cord Injury[J]. Journal of Liaoning Medical University (LNMU) Bimonthly, 2012, 33(4): 301-302,385,386 |
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| Authors: | LIU Hao ZOU Lian LI Hangxu ZHANG Xiaoyi ZHANG Ziliang |
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| Affiliation: | 1.Liaoning Medical University,Jinzhou 121001 China; 2.The Second Artillery General Hospital,Beijing 100088 China) |
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| Abstract: | Objective To investigate the expression of nerve growth factor receptor P75 in prostate and bladder of rats with spinal cord injury.Methods A model of 40 rats with spinal cord injury was built and 30 normal rats were chosen into the control group.The changes of P75 in prostate and bladder tissues of the rats were measured by using the immunohistochemistry and image-analysis technique.Results The expression of P75 in both prostate and bladder in the model of rats with spinal cord injury were significantly lower than those in the control group and the difference had statistic significance.Conclusion Spinal cord injury caused the decrease of nerve growth factor receptor P75 in bladder and prostate to some extent. |
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| Keywords: | spinal cord injury P75 bladder prostate |
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