A unique case of ovarian psammocarcinoma with mediastinal,pulmonary, subcutaneous,and omental metastases |
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Authors: | Daniel M Chase Dorothy A Sparks Melissa Gener James Smith |
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Institution: | (1) Department of Surgery, Western Reserve Care System/Northeast Ohio Universities College of Medicine, 500 Gypsy Lane, Youngstown, OH 44505, USA;(2) Department of Pathology, Western Reserve Care System/Northeast Ohio Universities College of Medicine, 500 Gypsy Lane, Youngstown, OH 44505, USA |
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Abstract: | Psammocarcinoma is a rare form of serous ovarian and peritoneal carcinoma, characterized by abundant psammoma bodies, invasiveness,
and low-grade cytological features. Many of the cases which have been reported had extraovarian spread and peritoneal seeding
at the time of presentation. We present a case of 45-year-old woman with ovarian psammocarcinoma who initially presented with
a metastatic subcutaneous nodule, and was found to have pulmonary and mediastinal metastases. We believe this to be the first
report of a psammocarcinoma with these metastases. Ovarian and peritoneal psammocarcinomas are quite rare, and because of
this, knowledge of their behavior is limited. Although most seem to follow an indolent course similar to that of borderline
lesions of the ovary, this case demonstrates that some of these tumors may be clinically aggressive with distant metastases. |
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Keywords: | Psammocarcinoma Mediastinal Ovarian Carcinoma Psammoma bodies |
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