| 氟虫腈的毒理学研究进展 |
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| 引用本文： | 张芳芳,洪雅青,张幸.氟虫腈的毒理学研究进展[J].职业与健康,2008,24(20):2211-2213. |
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| 作者姓名： | 张芳芳 洪雅青 张幸 |
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| 作者单位： | 浙江省医学科学院卫生学研究所,杭州市,310013 |
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| 摘 要： | 氟虫腈是以γ-氨基丁酸（GABA）受体为靶标的苯基吡唑类杀虫剂，广泛应用于农业、果业和家庭卫生。该文从动物实验、人类健康及环境危害3个方面就氟虫腈的毒性研究作一综述，探讨氟虫腈的毒作用机制，并提出目前评价氟虫腈对人类危害存在的新问题。
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| 关 键 词： | 氟虫腈 GABA受体 神经毒性 生殖毒性 环境毒理学 |
Advance in Toxicological Study on Fipronil |
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| ZHANG Fang-fang,HONG Ya-qing,ZHANG Xing.Advance in Toxicological Study on Fipronil[J].Occupation and Health,2008,24(20):2211-2213. |
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| Authors: | ZHANG Fang-fang HONG Ya-qing ZHANG Xing |
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| Institution: | ( Zhejiang Health Academy of Medical Sciences Institute, Zhefiang, 310013, China ) |
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| Abstract: | Fipronil, a kind of phenylpyrazolo pesticide, tookγ-aminobutyric acid （ GABA ） receptors as target, was widely used in agriculture, fruit industry and family health. This paper summarized the toxicity of fipronil on three aspects ： animal experiments, hu- man health and environmental hazards, explored the toxic mechanism of fipronil and put forward the existed new problems of fipronil harm evaluation to human. |
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| Keywords: | Fipronil GABA receptor Neurotoxicity Reproductive toxicity Environment toxicology |
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