| 提高骨组织工程支架材料生物相容性的关键影响因素 |
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| 引用本文： | 吴巧凤,陈槐卿.提高骨组织工程支架材料生物相容性的关键影响因素[J].国际生物医学工程杂志,2007,30(2):104-108. |
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| 作者姓名： | 吴巧凤 陈槐卿 |
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| 作者单位： | 1. 610075,成都中医药大学针灸推拿学院
2. 610041,成都,四川大学华西医学中心生物医学工程实验室 |
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| 基金项目： | 国家高技术研究发展计划(863计划)资助项目(2002AA326080) |
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| 摘 要： | 骨组织工程领域除了对支架材料本身的构成和性能加以研究之外，其研究范围还包括：对支架材料的孔径、孔隙率及三维相通性的研究；种子细胞的筛选、生物活性因子的参与以及生物复合材料的构建等相关因素的研究，这些因素对支架材料的生物相容性以及体内的骨传导性和骨诱导性都至关重要。从这些方面人手，有可能使骨组织工程支架材料的发展取得长足的进步。
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| 关 键 词： | 骨组织工程 支架材料 种子细胞 生物相容性 |
Key factors for improving the biocompatibility of tissue engineering scaffolds |
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| WU Qoao-feng,CHEN Huai-qing.Key factors for improving the biocompatibility of tissue engineering scaffolds[J].International Journal of Biomedical Engineering,2007,30(2):104-108. |
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| Authors: | WU Qoao-feng CHEN Huai-qing |
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| Abstract: | Ideal bone tissue engineering compounds should possess good biocompatibility and three dimensional porous structures as well as assuring mechanical properties. In addition, the participating of biologically active factors and constructing of the composite could be key factors for improving the osteo-conductivity and osteo-inductivity of scaffold materials. By paying more attentions to these aspects, researchers will be able to get quiet great progress in the development of tissue engineering scaffold materials. |
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| Keywords: | bone tissue engineering scaffolds seeding cells biocompatibility |
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