| 甲状旁腺功能亢进症的免疫组化和流式细胞学研究 |
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| 引用本文： | 潘晓琳,小出直彦,小林信也,小林克.甲状旁腺功能亢进症的免疫组化和流式细胞学研究[J].农垦医学,1994(3). |
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| 作者姓名： | 潘晓琳 小出直彦 小林信也 小林克 |
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| 作者单位： | 石河子医学院病理学教研室(潘晓琳)，日本信州大学医学部(小出直彦，小林信也，小林克) |
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| 摘 要： | 应用抗Brdu和Ki—67两种单克隆抗体及免疫组化ABC法对29例甲状旁腺功能亢进症患者的甲状旁腺组织进行细胞增殖活力的测定,并将两种标记指数和流式细胞术的细胞周期时相分析进行对比。结果显示:1.免疫组化技术对于甲旁亢细胞增殖活力的测定优于流式细胞技术,可能提供更加客观和可信的指标。2.功能亢进的甲状旁腺细胞可能具有低增殖活力的生物学特性。
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| 关 键 词： | 甲状旁腺功能亢进症 免疫组织化学 流式细胞术 细胞增殖活力 |
ASSESSMENT OF PROLIFERATIVE ACTIVITY OF GLANDULAR CELLS IN HYPERPARATHYROIDISM USING IMMUNOHISTOCHEMICAL AND FLOW CYTOMETRIC METHODS |
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| Pan Xiao lin,Naohiko Koide,Shiya Kobayashi,Masaru Kobayashi,Futoshi Iida.ASSESSMENT OF PROLIFERATIVE ACTIVITY OF GLANDULAR CELLS IN HYPERPARATHYROIDISM USING IMMUNOHISTOCHEMICAL AND FLOW CYTOMETRIC METHODS[J].Agricultural Reclamation Medicine,1994(3). |
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| Authors: | Pan Xiao lin Naohiko Koide Shiya Kobayashi Masaru Kobayashi Futoshi Iida |
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| Institution: | Pan Xiao lin Naohiko Koide Shiya Kobayashi Masaru Kobayashi Futoshi Iida |
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| Abstract: | We measured the cellular proliferation of 29 hyperfunctioning parathyroid glands using immunohistochemistry and flow cytometry and found; 1. Immunohis-tochemistry with Brdu and Ki -67 monoclonal antibodies may be an objective and reliable indicator in studing the proliferative activity of hyperfunctioning parathyroid glands. 2. The glandular cells of hyperfunctioning parathyroid diseases have a property characteristized byslow cell cycle. |
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| Keywords: | hyperparathyroidism immunohistochemistry flow cytometry proliferative activity |
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