| 刺五加注射液对小鼠急性心肌缺氧的保护作用 |
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| 引用本文： | 许善初,陶明飞.刺五加注射液对小鼠急性心肌缺氧的保护作用[J].中国临床药理学与治疗学,2004,9(6):713-716. |
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| 作者姓名： | 许善初 陶明飞 |
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| 作者单位： | 1. 蚌埠医学院附属医院药剂科
2. 蚌埠医学院附属医院机能实验中心,蚌埠,233003,安徽 |
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| 摘 要： | 目的 :观察刺五加对小鼠急性心肌缺氧的保护作用。方法 :常压和低压缺氧条件下分别观察小鼠平均存活时间和心肌耗氧量。结果 :刺五加注射液高低剂量组均可使小鼠常压和低压条件下平均存活时间延长 ;降低常压、低压条件下心肌耗氧量。结论 :刺五加注射液能明显降低小鼠心肌氧耗 ,提高小鼠抗应激能力 ,保护缺氧心肌
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| 关 键 词： | 刺五加 心肌缺氧 抗应激 小鼠 |
| 文章编号： | 1009-2501(2004)06-0713-04 |
| 修稿时间： | 2004年3月2日 |
Protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia |
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| XU Shan-Chu,TAO Ming-Fei.Protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2004,9(6):713-716. |
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| Authors: | XU Shan-Chu TAO Ming-Fei |
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| Institution: | XU Shan-Chu,TAO Ming-Fei 1 Department of Pharmacy,Affiliated Hospital, 1 Function Experimental Centre,Bengbu Medical College,Bengbu 233003,Anhui,China |
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| Abstract: | AIM: To observe the protective effect of Acanthopanecis senticosus injection in rats with acute myocardial hypoxia. METHODS: The mean survival time and capacity for myocardial oxygen consumption were detected in rats with acute hypoxia under ordinary or low pressure. RESULTS: Various dosages of Acanthopanecis senticosus injection could prolong the mean survival time and reduce capacity for myocardial oxygen consumption in rats with acute hypoxia under ordinary or low pressure. CONCLUSION: The Acanthopanecis senticosus injection can evidently reduce capacity for myocardial oxygen consumption and increase ability to anti-stress and plays a protective role in rats with hypoxic myocardium. |
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| Keywords: | Acanthopanecis senticasi myocardial hypoxia anti-stress rats |
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