血清心肌酶检测在中枢神经系统感染诊断中的意义

目的 探讨血清心肌酶检测在中枢神经系统感染患者中的临床意义,为中枢系统感染的诊断及预后评价提供依据.方法 中枢神经系统感染患者68例.另外,选取同时间健康体检的60例作为对照组.分别检测两组的血清天冬氨酸氨基转移酶（AST）、乳酸脱氢酶（LDH）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）水平.结果 中枢神经系统感染组的AST、LDH、CK以及CK-MB等四种酶间的含量均远高于对照组（P＜0.05）.中枢神经系统感染重型组AST、LDH、CK以及CK-MB等四种酶的含量也均高于对照组（P＜0.05）.结论 中枢神经系统感染患者的血清心肌酶水平显著升高,且血清心肌酶的水平与严重程度之间呈正比.血清心肌酶是一个中枢神经系统感染的可靠诊断指标.

The detection and significance of serum enzymes in the adult with central nervous system infections

Objective To study the serum enzyme in the adult central nervous system infection in patients and its clinical significance,aimed at providing basis for the diagnosis and prognosis of the adult central nervous system infection. Methods 68 patients with central nervous system infections were treated in June 2008 to Decem 2009 in Neurology Department of our hospital. In addition, 60 healthy persons were selected at the same time as control group. Serum aspartate aminotransferase ( AST), lactate dehydrogenase ( LDH) , Creatine kinase ( CK) , CK-MB ( CK-MB)levels were detected. Results AST,LDH,CK and CK-MB levels of the central nervous system infection group were higher than the control group,and the difference between the two groups was statistically significant(P<0.05). Severe group AST, LDH, CK and CK-MB and other content of the four enzymes were higher, and the difference between the two groups is also significant ( P < 0.05 ). Conclusions Adult patients with central nervous system infection significantly increased serum enzyme levels, and serum enzyme levels had a positive correlation with the severity. Serum enzyme was a reliable adult central nervous system infections diagnostic index.