| 痢止蒿化学成分的研究 |
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| 引用本文： | 王爱国,吕扬,冯孝章. 痢止蒿化学成分的研究[J]. 药学学报, 1994, 29(12): 899-904 |
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| 作者姓名： | 王爱国 吕扬 冯孝章 |
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| 作者单位： | 中国医学科学院，中国协和医科大学药物研究所 |
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| 摘 要： | 自云南产痢止蒿(Ajuga forrestii Diels)全草的乙醇提取物中分得5个单体,其中化合物Ⅰ和Ⅱ经波谱分析和化学方法鉴定为新的松香烷型二萜类化合物,分别命名为痢止蒿甲素(ajuforrestin A,I)和痢止蒿乙素(ajuforrestin B,II),其余3个是黄酮类化合物:洋芹素(apigenin)、金合欢素(acacetin)和买麻藤乙素(gnetifolin B)。
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| 关 键 词： | 痢止蒿 松香烷二萜 痢止蒿甲素 痢止蒿乙素 |
| 收稿时间： | 1993-12-06 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF AJUGA FORRESTII DIELS |
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| AG Wang,Y Lu and XZ Feng. STUDIES ON THE CHEMICAL CONSTITUENTS OF AJUGA FORRESTII DIELS[J]. Acta pharmaceutica Sinica, 1994, 29(12): 899-904 |
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| Authors: | AG Wang Y Lu XZ Feng |
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| Abstract: | Two new abietane type diterpenoids,ajuforrestin A and B have been isolated fromthe whole plant materials of Ajuga forrestii Diels. Their structures ,12 ,16-epoxy-11,14-dihydroxy-3,5,8,11,13,15-abietahexaene-7-one and 12,16-epoxy-11,14-dihydroxy-3,5,8,11,13-abietapentaene-7-one were established by spectroscopic means and comparison with closely relatedcompounds.The structure of ajuforrestin A was also confirmed by single-crystal X-ray analysis.Three known flavonols,apigenin,acacetin and gnetifolin B were also obtained. Gnetifolin B was firstisolated from the Ajuga genus. |
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| Keywords: | Abietane diterpenoid Ajuforrestin A Ajuforrestin B Ajuga forrestii Diels |
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