虹膜组织力学特性的实验研究

目的 模拟眼内前后房压强差，对人眼和兔眼虹膜整体加压，研究其力学特性。方法将瞳孔水密缝合，不破坏其几何形态，对虹膜整体加压。结果 首次实现了对虹膜整体力学特性的认识，人眼和兔眼虹膜力学特性相似，虹膜是典型的粘弹性物质，面积模量与前后房压强差之间基本呈线性关系，并且在相同的前后房压强差下人眼虹膜的面积模量比兔眼虹模的略小。结论 实验结果可为青光眼致盲机理解释和瞳孔阻滞力的估算提供参考；同时，经适当修正后，兔虹膜可作为人虹膜力学特性的研究样本，大大降低研究成本。

An Experimental Study on Biomechanical Properties of Iris Tissue

Objective The biomechanical properties of iris tissues of both the rabbit and the human being have been measured with the method of the whole pressurrization developed by us, and with the method of stimulating the difference of pressure between anterior chamber and posterior chamber in eyes. Methods The pupils are sewn for being water-proof without altering its geometrical shape to make the iris into a part of the glomeration. Then, we impose pressure on the whole iris. Results The iris materials is visco-elastic. These properties are available for the first time. Furthermore, the results show that similarity in biomechanical properties existed between the rabbit iris and the human iris. Linear relation on the whole existed between the area modulus and the difference of pressure between anterior chamber and the posterior chamber in the eye. Under the same pressure difference the area modulus and the curvature radius of the human iris are a little less than those of the rabbit iris. Conclusion The results will be useful in explaining glaucoma and in estimating the Pupillary Blocking Force. Through proper adjustment the rabbit iris can be used as a substitute in studying the biomechanical properties of the human iris with great cost reduction.