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Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma
Authors:S. G. Tsikunov  N. N. Klyueva  A. G. Kusov  T. V. Vinogradova  V. M. Klimenko  A. D. Denisenko
Affiliation:(1) I. P. Pavlov Department of Physiology, Department of Biochemistry, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg
Abstract:The concentration of high-density lipoprotein cholesterol and triglycerides in rat serum sharply decreased after psychic trauma caused by life hazard. The content of these substances remained unchanged for not less than 1 week after trauma. The concentration of high-density lipoprotein cholesterol was low, while serum content of triglycerides increased 6 weeks after trauma. The concentration of high-density lipoprotein cholesterol significantly decreased after repeated psychic trauma. These changes were accompanied by a sharp increase in the concentration of triglycerides in the serum. Total cholesterol concentration in the liver decreased under these conditions. __________ Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 141, No. 5, pp. 575–578, May, 2006
Keywords:psychic trauma  cholesterol  triglycerides  high-density lipoprotein cholesterol
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