Changes in the lipid composition of blood plasma and liver in rats induced by severe psychic trauma |
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Authors: | S. G. Tsikunov N. N. Klyueva A. G. Kusov T. V. Vinogradova V. M. Klimenko A. D. Denisenko |
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Affiliation: | (1) I. P. Pavlov Department of Physiology, Department of Biochemistry, Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg |
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Abstract: | The concentration of high-density lipoprotein cholesterol and triglycerides in rat serum sharply decreased after psychic trauma caused by life hazard. The content of these substances remained unchanged for not less than 1 week after trauma. The concentration of high-density lipoprotein cholesterol was low, while serum content of triglycerides increased 6 weeks after trauma. The concentration of high-density lipoprotein cholesterol significantly decreased after repeated psychic trauma. These changes were accompanied by a sharp increase in the concentration of triglycerides in the serum. Total cholesterol concentration in the liver decreased under these conditions. __________ Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 141, No. 5, pp. 575–578, May, 2006 |
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Keywords: | psychic trauma cholesterol triglycerides high-density lipoprotein cholesterol |
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