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联合检测血清中ADA、GGT和AFU对肝癌患者诊断的临床意义
引用本文:林莉,林美玲.联合检测血清中ADA、GGT和AFU对肝癌患者诊断的临床意义[J].海南医学院学报,2011,17(3):328-329,338.
作者姓名:林莉  林美玲
作者单位:1. 广东省中医院二沙分院检验科,广东,广州,510105
2. 中山大学附属第三医院检验科,广东,广州,510630
基金项目:海南医学院科研基金资助学报项目
摘    要:目的:检测腺苷脱氨酶 (ADA)、γ谷氨酰转移酶(GGT)和α-L-岩藻糖苷酶(AFU)在肝癌患者血清中的含量,探讨其联合检测的意义.方法:本实验以76例肝癌患者的血清标本作为A组,选取76例肝硬化患者作为B组,选取76例肝炎患者作为 C 组,选取76例健康体检成人作为D组,检测四组血清中 ADA、GGT和AFU的含量...

关 键 词:肝癌  腺苷脱氨酶  γ谷氨酰转移酶  α-L-岩藻糖苷酶

Predictive value of combined detection of serum ADA, GGT, and AFU in diagnosis of hepatocarcinoma
LIN Li,LIN Mei-ling.Predictive value of combined detection of serum ADA, GGT, and AFU in diagnosis of hepatocarcinoma[J].Journal of Hainan Medical College,2011,17(3):328-329,338.
Authors:LIN Li  LIN Mei-ling
Institution:1.Laboratory Department,Ersha Branch of Guangdong Provincial Hospital,Guangzhou,510105;2.Laboratory Department,The third Affiliated Hospital of Zhongshan University,Guangzhou 510630,China)
Abstract:Objective:To detect the serum levels of adenosine deaminase(ADA),γ glutamyl transferase(GGT) and α-L-fucosidase(AFU) hepatocarcinoma patients to explore its predictive value in the diagnosis of hepatocarcinoma.Methods:Blood samples of hepatocarcinoma cases(group A,n=76),liver cirrhosis patients(group B,n=76),hepatitis patients(group C,n=76) andcontrol healthy volunteers(group D,n=76) were collected and detected for the ADA,GGT and AFu levels in order to explore the correlation between these parameters and pathological characters of different live diseases.Results:Levels of ADA,GGT,and AFU was significant higher in hepatocarcinoma patients than that in hepatitis or cirrhosis patients,of the latter two,levels in cirrhosis patients was higher.Levels of ADA,GGT and AFU were positively correlated to the size and stage of the tumor for patients with hepatocarcinoma.Conclusions:Combined detection of ADA,GGT,and AFU levels probably can predict the onset and progress of hepatocarcinoma.
Keywords:Hepatocarcinoma  Adenosine deaminase  γ-glutamyl transferase  α-L-fucosidase
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