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新生儿脐血浆内皮素与妊高征的关系
引用本文:张丙宏,田鸾英,王彩霞.新生儿脐血浆内皮素与妊高征的关系[J].武汉大学学报(医学版),2002,23(2):188-189.
作者姓名:张丙宏  田鸾英  王彩霞
作者单位:1. 武汉大学人民医院,儿科,武汉,430060
2. 武汉大学人民医院,妇产科,武汉,430060
摘    要:目的 :探讨新生儿脐血浆内皮素 (ET)水平与妊高征严重程度的关系。方法 :应用放射免疫法分别对 31例妊高征孕妇的新生儿 ,10例正常妊娠妇女的新生儿脐血浆ET水平测定。结果 :妊高征孕妇的新生儿脐血浆ET水平明显高于正常孕妇的新生儿 (P <0 .0 5 ) ,但在妊高征Ⅲ度之间无明显差异 (P >0 .0 5 )。结论 :妊高征引起的ET升高是导致胎儿宫内窘迫的重要原因之一。无论妊高征的严重程度如何都会引起新生儿血浆ET水平的升高

关 键 词:妊高征  婴儿  新生  内皮素
修稿时间:2001年4月18日

Determination of Unbilical Plasma Endothelin Levels in Neonates Born by PIH Women
Zhang Binghong,Tian Luanying,Wang Caixia.Determination of Unbilical Plasma Endothelin Levels in Neonates Born by PIH Women[J].Medical Journal of Wuhan University,2002,23(2):188-189.
Authors:Zhang Binghong  Tian Luanying  Wang Caixia
Institution:Zhang Binghong,Tian Luanying,Wang Caixia Department of Pediatrics,Renmin Hospital,Wuhan University,Wuhan 430060,China
Abstract:Objective: To explore the relationship between unbilical plasma endothelin(ET) levels in neonates born by women suffered by pregnancy induced hypertension(PIH) and the severity of PIH. Methods: In the PIH group, neonates(n=31) were born by PIH women. In the control group, neonates were born by normal pregnancy women. Radioimmunological technique was used to determine ET levels. Results: We found that ET levels were much higher in the PIH group than those of the control group(P<0.05). But there weren't any differences among the mild, moderate, severe PIH cases(P>0.05). Conclusion: We infer that elevations of ET levels induced by PIH be an important factor for the development of intrauterine distress. Regardless of the severity of PIH, there would be an increase in ET levels.
Keywords:pregnancy induced hypertension  infant  newborn  endothelin
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