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| 缓激肽在大鼠局灶性脑缺血区的分布 | |
| 引用本文： | 沈宝林,沈宏友,杜韵璜,黎昭洪. 缓激肽在大鼠局灶性脑缺血区的分布[J]. 解剖学研究, 2002, 24(2): 108-109,122,I002 |
| 作者姓名： | 沈宝林 沈宏友 杜韵璜 黎昭洪 |
| 作者单位： | 1. 广东药学院解剖学教研室,广州,510224 2. 第一军医大学分校 3. 暨南大学医学院 |
| 摘 要： | 目的 研究缓激肽 (BK)在大鼠局灶性脑缺血区的分布。方法 应用免疫细胞化学方法 ,结合光学显微镜观察缓激肽在大鼠局灶性脑缺血的分布。结果 脑缺血 3h后 ,大鼠损伤侧MCA分布区的神经细胞中 ,发现BK样免疫阳性反应物 ;而正常大鼠MCA供血区的神经细胞内未见有BK样免疫阳性反应物。结论 正常大鼠MCA分布区的神经细胞内不存在或存在非常少的BK ,但在缺血性损伤后 ,神经细胞内出现较多的Bk。 |
| 关 键 词： | 缓激肽 脑缺血 大鼠 |
Distribution of bradykinin in rat''''s focal cerebral ischemic region |
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| Shen Baoling,Shen Hongyou,Du Yunhuang,Li Zhaohong. Distribution of bradykinin in rat''''s focal cerebral ischemic region[J]. Anatomy Research, 2002, 24(2): 108-109,122,I002 | |
| Authors: | Shen Baoling Shen Hongyou Du Yunhuang Li Zhaohong |
| Affiliation: | Shen Baoling,Shen Hongyou,Du Yunhuang,Li Zhaohong. Department of Anatomy,Guangdong College of Pharmacy,Guangzhou,510224 China |
| Abstract: | Objective To investigate distribution of bradykinin in rats focal cerebral ischemic region. Method The immunocytochemical localization of bradykinin in rats focal cerebral ischemic region was observed by using optical microscope. Result The bradykinin like immunoreactivity positive substances were discovered in neurons in ischemic injury neocortex of middle cerebral artery(MCA) distributed region at 3rd hour after cerebral ischemia,but it were not discovered in the same region of normal control rat brains. Conclusion Little bradykinin exist in the neurons of the neocortex of MCA distributed region in nature rats,but much bradykinin appear after ischemic injury. |
| Keywords: | Bradykinin Cerebral ischemia Rat |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |