Late toxic effects of long-term exposure to lindane in peripheral blood cells in rabbits. II. Erythrocyte changes. |
| |
| Authors: | M Grabarczyk J Wo?niak U Podstawka J Kope?-Szlezak |
| |
| Affiliation: | Department of Physiopathology, Institute of Haematology, Warszawa, Poland. |
| |
| Abstract: | After lindane administration in daily doses of 0.1 LD50 for one month (total dose 2.0 LD50) changes in the erythrocytes were found persisting for up to 4 months after withdrawal of the pesticide. A significant increase in the number of echinocytes, a greater per cent of reticulocytes, significantly raised level of denatured haemoglobin, and an increased number of erythrocytes of higher sensitivity to oxidating factors in relation to control group was observed. |
| |
| Keywords: | |
|
|
