二地鳖甲煎联合他达拉非治疗糖尿病性勃起功能障碍35例

目的?探讨二地鳖甲煎联合小剂量他达拉非治疗糖尿病性勃起功能障碍（DED）的临床疗效。方法?选取70例DED患者，随机将其分为治疗组和对照组各35例，治疗组给予二地鳖甲煎汤剂每日1剂，分早晚2次口服，他达拉非片5?mg每晚1次口服，连续使用8周；对照组口服他达拉非片5?mg每晚1次，连续服用8周。治疗前后进行IIEF-5评分以及夜间阴茎勃起检查。结果?2组治疗后IIEF-5评分以及夜间阴茎勃起检查结果均有显著提高（P<0.01），治疗后治疗组优于对照组（P＜0.05）。2组均未出现严重不良反应。结论?二地鳖甲煎联合小剂量他达拉非治疗DED安全有效，值得临床推广。 

Erdi Biejia Decoction together with Tadalafil in Treating Diabetic Erectile Dysfunction: A Study of 35 Cases

OBJECTIVE?To discuss the clinical effect of Erdi Biejia decoction together with low dose of Tadalafil in treating diabetic erectile dysfunction. METHODS?70 patients with DED were randomly divided into two groups: the control group(35 cases) and the treatment group(35 cases). The treatment group was given Erdi Biejia decoction one dosage every day， orally taken in the morning and evening. Tadalafil pills(5mg) were orally taken once every night for eight weeks. The control group took Tadalafil pills(5mg) once every night for eight weeks. Before and after the treatment， IIEF-5 scores and nocturnal penile tumescence were recorded. RESULTS?After the treatment， IIEF-5 scores and nocturnal penile tumescence of both groups significantly improved(P<0.01). After the treatment， the treatment group performed better than the control group(P<0.05). So serious side effects showed in the two groups. CONCLUSION?Erdi Biejia decoction together with low dose of Tadalafil were effective in treating DED and were worth of being widely applied in clinical practices.