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“骨宝丸”防治佝偻病的实验研究
引用本文:陈燕平,陈训华,薛延,龚翠红,苗燕玲,邱明才. “骨宝丸”防治佝偻病的实验研究[J]. 中国骨伤, 1994, 7(5): 5-6
作者姓名:陈燕平  陈训华  薛延  龚翠红  苗燕玲  邱明才
作者单位:中国中医研究院骨伤科研究所,北京积水潭医院生化研究室,天津医学院附属医院内分泌研究所
摘    要:本文观察了佝偻病大鼠在用中药“骨宝丸”治疗前后血清钙、磷、碱性磷酸酶、25羟基维生素D3及骨组织形态学和骨计量学的变化,并与维生素D3进行了比较。结果表明:“骨宝丸”防治佝偻病有效,特别是在提高血钙、血磷和降低血碱性磷酸酶以及促进类骨质矿化方面效果显著,但其作用机理与维生素D3不同。

关 键 词:佝偻病,骨宝丸,预防与治疗

Experimental study on Gu Bao Wan in treating rachitis
Chen Yanping,Chen Xunhua. Experimental study on Gu Bao Wan in treating rachitis[J]. China journal of orthopaedics and traumatology, 1994, 7(5): 5-6
Authors:Chen Yanping  Chen Xunhua
Affiliation:Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700;Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700;Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700;Institute of Orthopoedics & Traumatology,China Academy of Traditional Chinese Medicine 100700
Abstract:In this article,changes of serum calcium.phosphorus.alkaline phosphatase,25-hydroxy-vitamin D3,bone tissue morphology and bone metrology were observed in treating rachitic rats with Chinese medicine Gu Bao Wan pre-and post-treatment and they were compared with Vitamin D3.The results indicated that Gu Bao Wan is effective in the prevention and treatment of rachitis,especially it has prominent effects in the elevation of serum calcium,phosphorus,and decreasing of serum alkaline phosphatase and in the promotion of mineralization of osteoid.But it is different from the mechanism of Vitamin D3.
Keywords:Rachitis Gu Bao Wan Prevention and treatment
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