Frequent importation of enterovirus 71 from surrounding countries into the local community of Yamagata, Japan, between 1998 and 2003 |
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| Authors: | Mizuta K Abiko C Murata T Matsuzaki Y Itagaki T Sanjoh K Sakamoto M Hongo S Murayama S Hayasaka K |
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| Institution: | Department of Microbiology, Yamagata Prefectural Institute of Public Health, Tokamachi 1-6-6, Yamagata, 990-0031 Japan. mizutak@pref.yamagata.jp |
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| Abstract: | Phylogenetic analysis of 45 enterovirus 71 (EV71) isolates for 6 years in Yamagata, Japan, clarified that the annual outbreak of hand-foot-and-mouth disease was due to four genetically distinct subgenogroups, including a novel "B5." Our results suggest that the importation of EV71 from surrounding countries has had a major epidemiological impact on the local community used in our study. |
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