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Chronic recurrent multifocal osteomyelitis in a patient with selective immunoglobulin M deficiency
Authors:Balahan Makay  Erbil Ünsal  Özden Anal  Dilek Güneş  Süleyman Men  Handan Çakmakçı  Erdener Özer
Affiliation:(1) Department of Pediatrics, Dokuz Eylul University Hospital, 35340 Balcova-Izmir, Turkey;(2) Department of Radiology, Dokuz Eylul University Hospital, Balcova-Izmir, Turkey;(3) Department of Pathology, Dokuz Eylul University Hospital, Balcova-Izmir, Turkey
Abstract:Chronic recurrent multifocal osteomyelitis is an unusual inflammatory process of unknown origin involving multiple osseous sites, often recurrently. Selective immunoglobulin M (IgM) deficiency is a rare primary immunodeficiency disease, which can be associated with autoimmune diseases such as systemic lupus erythematosus, Hashimoto’s disease, or hemolytic anemia. Here we report a case of a chronic recurrent multifocal osteomyelitis coexisting with selective IgM deficiency.
Keywords:Chronic recurrent multifocal osteomyelitis  Selective IgM deficiency
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