Alterations in outer membrane proteins of Pseudomonas aeruginosa associated with selective resistance to quinolones. |
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| Authors: | G L Daikos V T Lolans and G G Jackson |
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| Institution: | Department of Medicine, University of Illinois College of Medicine, Chicago 60680. |
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| Abstract: | Electrophoresis of outer membrane proteins in three ciprofloxacin-resistant strains of Pseudomonas aeruginosa isolated during therapy and their in vitro revertants indicated that diminution or loss of a 31- to 32-kilodalton outer membrane protein correlated with resistance in two of the three isolates. Resistance was unstable and caused no cross-resistance with other antibiotics. |
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