| 阿托品AF-DX116对兔膈神经放电的影响 |
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| 引用本文： | 洪小曼,印晓星,卞春甫.阿托品AF-DX116对兔膈神经放电的影响[J].徐州医学院学报,1991(1). |
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| 作者姓名： | 洪小曼 印晓星 卞春甫 |
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| 作者单位： | 徐州医学院神经药理研究室
(洪小曼，印晓星)，徐州医学院神经药理研究室(卞春甫) |
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| 摘 要： | 在清醒,肌松切断双侧迷走神经家兔,记录膈神经放电,观察小脑延髓池注射阿托品0.05mg/kg,0.1mg/kg,AF-DX1160.1mg/kg都使膈神经放电脉冲计数增多,幅度变大。结果表明:阿托品兴奋呼吸中枢可能和AF-DX116一样,与阻断M_2受体有关。
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| 关 键 词： | 呼吸中枢 膈神经放电 阿托品 AF-DX116 兔 |
EFFECTS OF ATROPINE AND AF-DX116 ON EFFERENT PHRENIC DISCHARGE |
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| Hong Xiaoman,et al.EFFECTS OF ATROPINE AND AF-DX116 ON EFFERENT PHRENIC DISCHARGE[J].Acta Academiae Medicinae Xuzhou,1991(1). |
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| Authors: | Hong Xiaoman |
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| Abstract: | In conscious, ragotomized, curarized and artificaily ventilated rabbits , the efferent Phrenic discharge was recorded. When atroPine 0.05 or O.lmg/ kg, or AF-DX116 O.lmg/kg was injected into the cerebello-medullary cistern, the frequency and amplitude of Phrenic discharges were increased. These results indicate that atroPine' s action on respiration may be attributed to the Possibility that it blocks the inhibitory M2 cholinergic receptor in respiratory center. |
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| Keywords: | respiratory centerd Phrenic discharge atropine AF-DX116 rabbits |
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