中心静脉导管相关性脓毒症

目的 了解导管相关性脓毒症（ＣＲＳ）的菌群分布及药敏情况。方法 对１９９３年２月至１９９７年１２期间发生的５２例中心静脉导管相关性脓毒症患者进行回顾性调查分析。结果 ＣＲＳ最常见的病原体是金黄色葡萄球菌和表皮葡萄球菌。大多数和细菌均有产高程度的耐药性。革兰阳性球菌对去甲万古霉素的敏感度达９３．３％,革单阴性杆菌对阿米卡星及头孢他啶的敏感率皆为５１．７％。结论 ＣＲＳ的有效处理方法是拔除感染的导管。

Nosocomial catheter-related sepsis secondary to central venous catheters

Objective To study bacteria and drug sensitivity of catheter related sepsis (CRS). Me thods Between February 1993 and December 1997,52 patients with central venous catheter related sepsis were studied retrospectively. Results The most common organisms were staphylococcus aureus and staphylococcus epidermis. The bacterial pathogens isolated demonstrated a marked pattern of antibiotic resistance. Gram positive cocci were sensitive to vancomycin with a sensitivity of 93 3%, and gram negative bacilli were sensitive to amikacin and ceftazidine with a sensitivity of 51 7%. Conclusions The effective treatment of catheter related sepsis is removal of infected catheters. Vancomycin and (or) amikacin may be first chosen to treat CRS.