| 甲状旁腺激素生理作用和构效关系研究 |
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| 引用本文： | 肖益热,刘景晶.甲状旁腺激素生理作用和构效关系研究[J].药学进展,2003,27(4):206-209. |
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| 作者姓名： | 肖益热 刘景晶 |
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| 作者单位： | 中国药科大学生化教研室,江苏,南京,210009 |
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| 摘 要： | 对甲状旁腺激素的生理作用及机制、分子结构、受体结合和构效关系等方面的研究作一综述，以期为开发新型骨质疏松症治疗药物提供理论依据。甲状旁腺激素是一种生理活性多肽，体内独特的成骨作用使其作为治疗骨质疏松症药物的研究日益深入。
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| 关 键 词： | 甲状旁腺激素 生理作用 分子结构 构效关系 |
| 文章编号： | 1001-5094(2003)04-0206-04 |
| 修稿时间： | 2003年4月4日 |
Studies on Physiological Function and Structure-activity Relationship of Parathyroid Hormone |
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| XIAO Yi-re,LIU Jing-jing.Studies on Physiological Function and Structure-activity Relationship of Parathyroid Hormone[J].Progress in Pharmaceutical Sciences,2003,27(4):206-209. |
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| Authors: | XIAO Yi-re LIU Jing-jing |
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| Abstract: | Parathyroid hormone (PTH) is a polypeptide with physiological activity. The unique bone forming activity in vivo of PTH prouides a theoretical basis for the researches of it as a drug for the treatment of osteoporosis increasingly advanced. The physiological function and mechanism, molecule structure, binding to the receptor and structure-activity relationship of PTH were reviewed in this article for discovering new therapeutics for the treatment of osteoporosis. |
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| Keywords: | Parathyroid hormone Physiological function Osteoporosis Structure-activity relationship |
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