Transient expression of c-fos during the development of the rat cerebral cortex |
| |
Authors: | C González-Martín I de Diego A Fairén B Mellstr?m J R Naranjo |
| |
Affiliation: | Instituto Cajal, CSIC, Madrid, Spain. |
| |
Abstract: | The present study has explored with immunocytochemical methods the expression of the proto-oncogene c-fos during the pre- and postnatal development of the cerebral cortex of the rat. The immunostaining of the Fos protein follows a strikingly precise spatiotemporal pattern: it occurs uniquely within layer VIb of the developing cerebral cortex, and is transient, lasting only from embryonic day 20 until postnatal day 1. The expression of c-fos in layer VIb may be related to the dynamic changes that occur at this level during development. |
| |
Keywords: | |
|
|