| Nd：YAG激光联合平阳霉素对兔耳静脉作用效应的研究 |
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| 引用本文： | 王丹丹,李永生.Nd：YAG激光联合平阳霉素对兔耳静脉作用效应的研究[J].临床口腔医学杂志,2009,25(7):406-408. |
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| 作者姓名： | 王丹丹 李永生 |
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| 作者单位： | 昆明医学院附属昆华医院·云南省第一人民医院口腔颌面外科,云南,昆明,650032 |
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| 摘 要： | 目的：探讨Nd：YAG激光联合平阳霉素（PYM）对兔耳静脉血管的作用效应。方法：健康新西兰白兔37只（74侧耳）随机分为A、B、C、D4组，A、B、C每组各12只，其中A组（实验组）每只兔耳注射PYM溶液0．3ml（浓度：4mg／ml），第7d后于注射段行Nd：YAG激光扫描照射（能量密度为2547．8J／cm^2）；B、C组（对照组）分别给予PYM注射、Nd：YAG激光扫描照射；D组（空白组）1只。A、B、C组于第1d、3d、7d、14d、21d、28d各取4只兔耳静脉组织行光镜观察，取第14d、28d组织行透射电镜观察。结果：①光镜下：A组与B组比较，14d、21d、28d的静脉损伤程度有显著性差异（P〈0．05）：A组与C组比较，7d、14d、21d、28d的静脉损伤程度有显著性差异（p〈0．05）。②电镜下：A组与B、C组比较，28d时仍可见内皮细胞水肿，内膜肿胀及附壁血栓。结论：Nd：YAG激光联合平阳霉素较单一处理对兔耳静脉的损伤程度重、损伤作用时间长。
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| 关 键 词： | Nd:YAG激光 平阳霉素 脉管畸形 |
Effects of combination of Nd:YAG laser and PYM to the veins of rabbit ears |
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| WANG Dan-dan,LI Yong-sheng.Effects of combination of Nd:YAG laser and PYM to the veins of rabbit ears[J].Journal of Clinical Stomatology,2009,25(7):406-408. |
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| Authors: | WANG Dan-dan LI Yong-sheng |
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| Institution: | WANG Dan-dan,LI Yong-sheng. Department of Oral , Maxillofacial Surgery,the First People Hospital of Yunnan Province,Yunnan Kunming 650032,China. |
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| Abstract: | Objective:The aim of the study was to investigate the lesion effects of combination of Nd:YAG laser and PYM to the veins of rabbit ears. Method:In the study of randomized block design,37 New Zealand white rabbits(74 ears in all)were divided into 4 groups(respectively named Group A,B,C,D). 12 in the Group A(Experiment Group),the normal vein of each rabbit ear was injected PYM 0.3 ml (Concentration is 4 mg/ml). Seven days after the injection,the same part of the vein was sweepingly irradiated by Nd:YAG laser ... |
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| Keywords: | Nd:YAG laser pingyangmycin/PYM vascular malformation |
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