红外线、He-Ne激光照射对CAG大鼠胃酸的影响

目的:探讨红外线、He-Ne激光对慢性萎缩性胃炎(CAG)大鼠胃酸的影响.方法:将63只成年雄性Wistar大鼠随机分成正常组、模型组,红外线组及各激光照射组.应用2%水杨酸钠和30%酒精的混合溶液灌胃8周,刺激大鼠胃粘膜,并结合劳累、饥饱失常等多因素方法建立大鼠CAG模型,照射组在建模完成后,分别给予红外线、不同剂量的He-Ne激光照射,每日一次.照射20天后,观察各组大鼠胃酸的变化.结果:红外线组及3.36 J/cm2的He-Ne激光组与模型组比较,胃酸分泌明显增多.结论:红外线及3.36J/cm2的He-Ne激光照射能够促进CAG大鼠的胃酸分泌,对大鼠CAG有较好的治疗作用.

The Effect of Infrared Rays and He-Ne Laser on Gastric Acid in Rat with Chronic Atrophic Gastritis

Purpose: To study the effect of infrared rays and He-Ne laser on gastric acid in Wistar rat with chronic atrophic gastritis. Method: Sixty-three adult male Wistar rats were randomly divided into six groups including normal control group, model group, infrared rays group and different doses He-Ne laser groups. We established CAG rats using enema with the mixed liquor which consisted of 2% sodium salicylate and 30% alcohol to stimulate rat's gastric mucosa, combined with irregular fasting and compulsive sporting as pathogenic factors. It was employed in treating CAG with infrared rays and different doses He-Ne laser for twenty days. Then collected diluted gastric acid for the determination of pH. Result: Compared with model group, there were distinctly different existed in infrared rays group and small dose He-Ne laser group (P<0.05). Conclusion: The irradiation of infrared rays and small dose He-Ne laser (3.36 J/cm2) had a good adjuvant therapeutic effect for the rat's CAG. After having been irradiated, there was obviously increase in gastric acid output.