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Two new coumarin glucosides from the roots ofangelica apaensis and their anti-platelet aggregation activity
Authors:Wei -Lie Xiao  Sheng-Hong Li  Yun -Heng Shen  Xue -Mei Niu  Han -Dong Sun
Affiliation:State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, China.
Abstract:Two new coumarin glucosides, 11-O-beta-D-glucopyranosyl thamnosmonin (1) and 12-O-beta-D-glucopyranosyl gosferol (2), were isolated from the roots of Angelica apaensis. Their structures were elucidated spectroscopically. Both compounds showed weak inhibitory effects on rabbit platelet aggregation induced by PAF, AA and APD.
Keywords:Anti-platelet aggregation  11-O-β  -D-glucopyranosyl thamnosmonin  12-O-β  -D-glu-copyranosyl gosferol  Coumarin   Angelica apaensis   Umbelliferae
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