Abstract: | We studied the effects of a new dipeptide with anxiolytic activity (GB-115, N-phenylhexanoyl-glycyl-L-tryptophan amide) on
parameters of the immune in intact mice and in animals with secondary immunodeficiency caused by cyclophosphamide. GB-115
in doses of 0.1–10 mg/kg stimulated phagocytic activity of peritoneal macrophages and humoral immune response in intact mice.
GB-115 exhibited immunocorrecting activity in animals with secondary immunodeficiency.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 5, pp. 548–551, May, 2008 |