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| 水溶性壳聚糖对肝癌细胞生长抑制的实验研究 | |
| 引用本文： | 周晚霞,黄国华,周南进,杨慧,俞红. 水溶性壳聚糖对肝癌细胞生长抑制的实验研究[J]. 江西医药, 2007, 42(11): 987-988 |
| 作者姓名： | 周晚霞 黄国华 周南进 杨慧 俞红 |
| 作者单位： | 1. 南昌大学第二附属医院 2. 江西省卫生学会办公室 3. 江西省医学科学研究所,南昌,330006 |
| 基金项目： | 江西省自然科学基金 , 江西省科技攻关项目 |
| 摘 要： | 目的 观察壳聚糖对肝癌细胞SMMC7721的生长抑制作用.方法 采用MTT法研究了不同浓度水溶性壳聚糖对肝癌细胞株SMMC7721的生长抑制作用.结果 水溶性壳聚糖可抑制肝癌细胞的生长,在一定范围内(50～400mg/L)呈剂量依赖关系.结论 水溶性壳聚糖对肝癌细胞的生长有抑制,并且呈剂量依赖关系. |
| 关 键 词： | 壳聚糖 肝癌细胞 生长抑制 水溶性 壳聚糖 肝癌细胞株 细胞生长抑制 实验 研究 cell lines human hepatocellular carcinoma chitosans 依赖关系 剂量 范围 结果 浓度 方法 抑制作用 |
| 收稿时间： | 2007-09-07 |
| 修稿时间： | 2007-11-19 |
The effects of water-solubility chitosans on antiproliferation in human hepatocellular carcinoma cell lines SMCC7721 |
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| Zhou WanXia,Huang Guohua, Zhou NanJin,et al. The effects of water-solubility chitosans on antiproliferation in human hepatocellular carcinoma cell lines SMCC7721[J]. Jiangxi Medical Journal, 2007, 42(11): 987-988 | |
| Authors: | Zhou WanXia Huang Guohua Zhou NanJin et al |
| Abstract: | Objective To study the effect of chitosans for Antiproliferation in hepatocellular carcinoma (HCC) cell lines(SMCC7721).Methods HCC line SMMC7721 was treated with different concentration of Water-solubility chitosan and antiproliferation effects was measured by MTT methed at 72h.Results Water-solubility chitosan had the effect of inhibition on the growth of hepatocarcinoma cells SMMC7721,which were enhanced along with increase of concentration in a range(50~400mg/L).Conclusion Chitosans could inhibit the growth of HCC cell line in vitro, and the inhibit was dose-depending . |
| Keywords: | chitosans hepatocellular carcinoma antiproliferation |
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