| 水溶性壳聚糖用于防感喷雾剂的澄清工艺研究 |
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| 引用本文： | 侯安国,王泽锋,李甲英,李安华.水溶性壳聚糖用于防感喷雾剂的澄清工艺研究[J].儿科药学杂志,2011,17(5):50-52. |
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| 作者姓名： | 侯安国 王泽锋 李甲英 李安华 |
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| 作者单位： | 1. 云南中医学院,云南昆明,650500
2. 云南省红河学院,云南蒙自,661100 |
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| 摘 要： | 目的:优选水溶性壳聚糖用于防感喷雾剂的最佳絮凝澄清工艺条件.方法:以连翘苷转移率和总苷含量作为评价指标,采用L9(34)正交实验设计优选防感喷雾剂最佳絮凝澄清工艺.结果:影响因素大小依次是:药液浓度>水溶性壳聚糖加入量>搅拌速度.最佳工艺的药液浓度生药∶药液=1.04∶5(g/mL),壳聚糖加入量为0.25 g/10....
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| 关 键 词： | 防感喷雾剂 壳聚糖 正交设计 连翘苷 |
Study on Flocculation Procedure with Chitosan for Fanggan Spray |
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| Hou Anguo,Wang Zefeng,Li Jiaying,Li Anhua.Study on Flocculation Procedure with Chitosan for Fanggan Spray[J].Journal of Pediatric Pharmacy,2011,17(5):50-52. |
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| Authors: | Hou Anguo Wang Zefeng Li Jiaying Li Anhua |
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| Institution: | Hou Anguo1,Wang Zefeng2,Li Jiaying1,Li Anhua1 (1.Yunnan University of Traditional Chinese Medicine,Yunnan Kunming 650500,China,2.Honghe University of Yunnan Province,Yunnan Mengzi 661100,China) |
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| Abstract: | Objective:To study the flocculation process with chitosan for Fanggan spray.Methods: The contents of forsythin and total glycosides were chosen as the assessment index.The optimum condition was selected by the L9(34) of orthogonal experiment.Results: The influence factors were in order the concentration of the extracting solution(A),the amount of chitosan(B) and stirring speed(C).The optimal flocculation process condition was A1B1C1.The medicinal materials and extract solution were 1.04∶5(g/mL),the added amount of chitosan was 0.25 g/10.4 g,the stirring speed was 200 r/min.Conclusions: The flocculation process with chitosan was effective and economic for the clarification and can be used for the purification of Fanggan spray. |
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| Keywords: | Fanggan spray Chitosan Orthogonal design Forsythin |
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