老年脑白质疏松与腔隙梗塞预后的关系

目的 :探讨脑白质疏松(LA)与腔隙梗塞(LI)预后的关系。方法 :将100例腔隙梗塞患者分为LI合并LA组(LI )及LI不合并LA组(LI-)。对两组患者卒中危险因素、卒中复发率、痴呆发生率、Barthel指数、病死率及死亡原因进行对比分析。结果 :随访结束时LI 组神经功能缺损评分、Barthel指数、卒中复发率、痴呆发生率及病死率与LI-组均有明显差异 ,P<0.01。结论 :LI合并LA者预后较差。

Leukoaraiosis and its relation with prognosis of lucunar infarction in elders

Objective: To evaluate whether leukoaraiosis (LA) influences lucunar infarction(LI) outcome. Methods:100 patients with LI were divided into two groups.One is LI with LA(LI ),the other is LI without it(LI-).Risk factors of stroke,the rate of recurrent stroke,the values of neurological defects,Barthel index,the prevalence of dementia and cause of death in two groups were compared.Results:In the end of the follow up period the rate of recurrent stroke,the values of neurological defects,the prevalence of dementia,the mortality were significantly higher in LI than LI- group.But Barthel Index was significantly lower in LI than LI- groups.None of 100 patients died of leukoaraiosis or lucunar infarction. Conclusion :The prognosis was less favorable in patients with LI than LI-.