| 线粒体一氧化氮合酶的研究进展 |
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| 引用本文： | 孙晓四,谭敦勇,王华东,颜亮. 线粒体一氧化氮合酶的研究进展[J]. 中国病理生理杂志, 2003, 19(12): 1700-1704 |
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| 作者姓名： | 孙晓四 谭敦勇 王华东 颜亮 |
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| 作者单位： | 暨南大学医学院病理生理学教研室, 广东 广州 510632 |
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| 基金项目： | 国家自然科学基金资助项目 (No .2 32 6 0 0 ) |
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| 摘 要： | Nitric oxide (NO) is an intra - and intercellular messenger with a broad spectrum of activities in the central nervous system, cardiovascular and immune systems. Mitochondrial nitric oxide synthase(mtNOS), which might be a new form of NOS in mitochondria, has been discovered to be active in the regulation of mitochondrial respiration, energy metabolism and manypathophysiological processes. In this review, the location, properties, physiological and pathophysiological significance of mtNOS were summarized.
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| 关 键 词： | 一氧化氮合酶 线粒体 |
| 文章编号： | 1000-4718(2003)12-1700-05 |
| 收稿时间： | 2003-03-02 |
| 修稿时间： | 2003-03-02 |
Progress in mitochondrial nitric oxide synthase |
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| SUN Xiao-si,TAN Dun-yong,WANG Hua-dong,YAN Liang. Progress in mitochondrial nitric oxide synthase[J]. Chinese Journal of Pathophysiology, 2003, 19(12): 1700-1704 |
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| Authors: | SUN Xiao-si TAN Dun-yong WANG Hua-dong YAN Liang |
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| Affiliation: | Department of Pathophysiology, Medical College of Jinan University, Guangzhou 510632, China |
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| Abstract: | Nitric oxide (NO) is an intra- and intercellular messenger with a broad spectrum of activities in the central nervous system, cardiovascular and immune systems. Mitochondrial nitric oxide synthase(mtNOS), which might be a new form of NOS in mitochondria, has been discovered to be active in the regulation of mitochondrial respiration, energy metabolism and many pathophysiological processes. In this review, the location, properties, physiological and pathophysiological significance of mtNOS were summarized. |
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| Keywords: | Nitric-oxide synthase Mitochondria |
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