| 化学和机械损伤对大鼠血管内皮细胞的影响 |
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| 引用本文： | 杨映波 王正国. 化学和机械损伤对大鼠血管内皮细胞的影响[J]. 中国病理生理杂志, 1993, 9(6): 727-730 |
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| 作者姓名： | 杨映波 王正国 |
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| 作者单位： | 第三军医大学第三附属医院创伤科，第三军医大学第三附属医院研究所四室，第三军医大学第三附属医院创伤科，第三军医大学第三附属医院研究所四室，第三军医大学第三附属医院创伤科，第三军医大学第三附属医院创伤科 重庆 630042，重庆 630042，重庆 630042，重庆 630042，重庆 630042 |
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| 摘 要： | 本文采用循环内皮细胞计数和扫描电镜观察等技术，研究了在化学性和机械性致伤条件下，大鼠（ｎ＝４０）血管内皮细胞脱落的程度和形态学改变。实验结果表明上述两种致伤因素均可导致循环内皮细胞显著增多和形态学变化。提示以酸性枸橼酸钠液致和钝性机械损伤大鼠尾静脉均可作为活体内研究血管内皮细胞损伤的实验模型。
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| 关 键 词： | 创伤 损伤 大鼠 血管 内皮 |
Effects of chemical and mechanical injury on vascular endothelial cells |
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| Yang Ying-Bo,Wang Zheng-Guo,et al Third Affiliated Hospital,Third Military Medical College,Chongqing. Effects of chemical and mechanical injury on vascular endothelial cells[J]. Chinese Journal of Pathophysiology, 1993, 9(6): 727-730 |
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| Authors: | Yang Ying-Bo Wang Zheng-Guo et al Third Affiliated Hospital Third Military Medical College Chongqing |
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| Abstract: | The effects of chemical and mechanical injury on vascullar endothelialcells have been studied in 40 rats, by using the techniques of circulating endothelial cells(CEC) count and scaning electromicroscope. The results showed that chemical and mech-anic injury caused desquamation markedly vascular endothelial cells (VEC). It was con-cluded that either scraping rat veins mechanically or injecting acidified 1.52% citratesolution via tail vein, both method can be used to study the VEC injuries in vivo. |
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| Keywords: | Wounds and injuries Rats Blood vessels Endothelium Cytometer |
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