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单抗-药物结合物的抗肿瘤研究现状
引用本文:白丽,钱金栿. 单抗-药物结合物的抗肿瘤研究现状[J]. 大理医学院学报, 1995, 0(2)
作者姓名:白丽  钱金栿
摘    要:免疫结合物又称免疫导向药物。由单克隆抗体、交联剂及抗癌制剂构成。它能特异地杀伤肿瘤细胞,而对正常细胞有很小的损伤作用。并能降低毒副作用。本文综述了单克隆抗休与化疗药物形成的免疫导向药物的抗肿癌作用及其存在的主要问题。

关 键 词:免疫结合物,单克隆抗体,化疗药物,癌症

Progress on Anti-tumour Effects of Monoclonal Antibody-drug Immunoconjugates
Bai Li et al. Progress on Anti-tumour Effects of Monoclonal Antibody-drug Immunoconjugates[J]. Journal of Dali Medical College, 1995, 0(2)
Authors:Bai Li et al
Affiliation:Bai Li et al
Abstract:Immunoconjugate is also called the immunotargeted drug,which consists of monoclonal antibodies,linkers and anti-cancer agents. It is sl specifically capable of killing tumour cells with little injuring effect on normal cells and decreasing toxic side effect of the agents. The antitumour effect and main problems of immunoconjugates formed by monoclonal antibodies and chemotherapeutic agents are reviewed i n this article.
Keywords:immunoconjugate  monoclonal antibody  chemotherapeutic agents  cancer
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