| 云芝多糖对小鼠肝脏超氧化物歧化酶活力和脂质过氧化的影响 |
| |
| 引用本文： | 魏文树,谭建权,陈海生. 云芝多糖对小鼠肝脏超氧化物歧化酶活力和脂质过氧化的影响[J]. 中国药理学与毒理学杂志, 1996, 0(4) |
| |
| 作者姓名： | 魏文树 谭建权 陈海生 |
| |
| 作者单位： | 第二军医大学药理学教研室(魏文树)，中国人民解放军福州医学高等专科学校(谭建权)，第二军医大学植物化学教研室(陈海生) |
| |
| 摘 要： | 云芝多糖对小鼠肝脏超氧化物歧化酶活力和脂质过氧化的影响魏文树１谭建权陈海生２（第二军医大学药理学教研室，上海２００４３３）云芝多糖（Ｃｏｒｉｏｌｕｓｖｅｒｓｉｃｏｌｏｒｐｏｌｙｓａｃｃｈａｒｉｄｅｓ，ＣＶＰ）系从长白山野生云芝中提取，含６７．５３％β...
|
| 关 键 词： | 多糖，云芝；超氧化物歧化酶；脂质过氧化；肝 |
Effects of Coriolus versicolor polysaccharides on superoxide dismutase activity and lipid peroxidation in mouse liver |
| |
| WEI Wen-Shu,TAN Jian-Quan,CHEN Hai-Sheng. Effects of Coriolus versicolor polysaccharides on superoxide dismutase activity and lipid peroxidation in mouse liver[J]. Chinese Journal of Pharmacology and Toxicology, 1996, 0(4) |
| |
| Authors: | WEI Wen-Shu TAN Jian-Quan CHEN Hai-Sheng |
| |
| Abstract: | The effects of Coriolus versicolorpolysaccharides (CVP) on superoxide dismutase (SOD) activity and lipid peroxidation in liver were studied in normal, tumor-bearing, and irradiated mice. CVP was administered ip daily for 3-9 d. It was shown that tumor burden and radiation resulted in decrease in SOD activity and increase in lipid peroxidation in mouse liver. CVP exerted enhancing effect on the SOD activity and suppressing effect on the lipid peroxidation not only in normal mice but also in tumor-bearing and irradiated mice. The results suggest that CVP is able to protect liver against lipid peroxidation by tumor growth and radiation. The inhibition of lipid peroxidation by CVP may be related to its effect on SOD activity. |
| |
| Keywords: | polysaccharides Coriolus versicolor (L.) Fr. superoxide dismutase lipid peroxidation liver |
| 本文献已被 CNKI 等数据库收录！ |
