急性心肌梗塞的性别差异

目的:分析急性心肌梗塞(AMI)病人死亡的性别差异。方法:对328例(其中男190例,女138例)AMI病人的临床资料,(包括年龄、性别、病史、并发症、血脂、血清酶水平进行分析。结果:女性死亡率高(17.3％vs6.8％,P<0.05),女性病例年龄高(69.10±10.00vs57.94±11.91,P<0.001),高血压史多(47.82％。vs34.21％,P<0.05),血脂水平高(5.73±1.38vs5.27±1.16mmol/L,P<0.001),血清磷酸肌酸激酶(CPK)峰值高(786.34±138.52vs648.32±113.8IU/mL,P<0.01)和非Q性心梗多(21.74％ vs12.63％ P<0.05),单变量死亡因素分析,高龄(年龄≥65岁),非Q性心梗,CPK峰值、休克、恶性心律失常和心力衰竭为死亡危险因素。结论:女性高死亡率与性别本身无关,而与年龄和梗塞范围有关。

Difference of Patients with Acute Myocardial Infarction in Sex

Objective: To get a clear understand of the difference in death of acute myocardial infarction (AMI)between men and women,Methods: To analyse the clinical laboratory parameters of 190 male patients and 138 female patients admitted to our hospital for AMI (including their age, sex, ill history, co-exist diseases, serum total cholesterol and serum creatin phosphokinase. Results: In comparison with men, the women were higher in inhospital mortality(17.3% vs 6.8%, .P < 0.01) ,older in age of undergoing the disease(69.10 ± 10.00 vs 57.94±11.91years old, P < 0.001), longer in hypertension history (47. 82% vs 34.21%,P<0.05),higher in serum total cholesterol level(5.73±1.38 vs 5.27± 1.16mmol/L, P<0.001) higher in peak of serum creatin phosphorinase (786.34±138.52 vs 648.32±113.8IU/mL P< 0.01)higher in incidence of non-Q-wave myocardial infarction (21.74% vs 12.63% ,P< 0.05) .There are six variable factors for inpatient death:old age( ≥65 years old), non-Q- ware myocardial infarction, high peak of CPK, shock , malignant arrhythmia and heart failure, Conclusion: The morality of acute myocardial infarction does not interrelate with the sex, but with the age and the extent of infraction.