| 柔茎香茶菜中的二萜化合物 |
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| 引用本文： | 刘旭,陈春霞,吴继洲. 柔茎香茶菜中的二萜化合物[J]. 中国中药杂志, 2022, 0(2): 433-436 |
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| 作者姓名： | 刘旭 陈春霞 吴继洲 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院药学部;华中科技大学同济医学院药学院;武汉软件工程职业学院 |
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| 基金项目： | 湖北省自然科学基金项目(2020CFB616)。 |
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| 摘 要： | 香茶菜属植物富含结构多样、新奇的对映,贝壳杉烷二萜及其衍生物,前期对柔茎香茶菜Rabdosia flexicaulis的化学成分研究尚不够系统,仅从中发现3个这类化合物.为了寻找结构新颖、活性显著的二萜化合物,采集了四川省道孚县的柔茎香茶菜地上部分,采用多种柱色谱法和波谱分析手段,从乙酸乙酯部位中分离并鉴定出6个二萜化...
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| 关 键 词： | 柔茎香茶菜 对映-贝壳杉烷 松香烷 二萜 |
Diterpenoids from Rabdosia flexicaulis |
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| LIU Xu,CHEN Chun-xia,WU Ji-zhou. Diterpenoids from Rabdosia flexicaulis[J]. China Journal of Chinese Materia Medica, 2022, 0(2): 433-436 |
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| Authors: | LIU Xu CHEN Chun-xia WU Ji-zhou |
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| Affiliation: | (Department of Pharmacy,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430040,China;School of Pharmacy,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430050,China;Wuhan Vocational College of Software and Engineering,Wuhan 430040,China) |
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| Abstract: | The genus Rabdosia is famous for the abundance of diverse and novel ent-kaurane diterpenoids.However,only a few ent-kauranoids have been discovered from R.flexicaulis since the investigation on its chemical constituents is not systematic.To find novel bioactive diterpenoids,the ethyl acetate extract of the above ground part of R.flexicaulis in Daofu County,Sichuan Province was obtained by column chromatography.One new compound and five known ones were identified as flexicaulin E(1),forrestin B(2),inf-lexarabdonin D(3),7α-hydroxydehydroabietic acid(4),15-hydroxydehydroabietic acid(5),and pomiferin F(6)by spectral techniques.Compounds 1-3 were the ent-kaurane diterpenoids isolated from this species for the first time.Compounds 4-6,aromatic abie-tanoids,were isolated from the genus Rabdosia for the first time. |
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| Keywords: | Rabdosia flexicaulis ent-kaurane abietane diterpenoid |
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