| 老年性痴呆的诊断进展 |
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| 引用本文： | 张颖冬.老年性痴呆的诊断进展[J].临床内科杂志,2003,20(12):621-624. |
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| 作者姓名： | 张颖冬 |
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| 作者单位： | 210029,南京,南京医科大学附属脑科医院神经内科 |
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| 摘 要： | 老年性痴呆(AD)是一种以痴呆为主要临床表现的脑变性疾病。目前早期诊断主要根据临床表现进行排除性诊断,缺乏客观的实验室指标作为“金标准”。本文就当前AD诊断方法研究进展,特别是生物学、神经影像学及电生理检查在AD诊断中的意义及其相应敏感性和特异性进行评述。
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| 关 键 词： | 老年性痴呆／诊断 神经影像学 |
| 文章编号： | 1001-9057(2003)12-0621-04 |
| 修稿时间： | 2003年9月26日 |
Advance in Alzheimer's disease diagnosis |
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| ZHANG Yingdong.Advance in Alzheimer's disease diagnosis[J].Journal of Clinical Internal Medicine,2003,20(12):621-624. |
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| Authors: | ZHANG Yingdong |
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| Institution: | ZHANG Yingdong,Department of Neurology,Nanjing Brain Hospital,Nanjing Medical University,Nanjing 210029,China |
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| Abstract: | Alzheimer's disease(AD)is a progressive neurodegenerative disorder of unknown etiology,characterized by irreversible dementia.Early diagnosis of AD depends now on the analysis of clinical manifestations and is fulfilled in an exclusive way.There are no objective markers to be as the "gold standard".According to the advance in AD study,the effects of biochemical markers,neuro-imaging and electrophysiological measurements,its sensitivity and specificity on the AD diagnosis is reviewed in this paper. |
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| Keywords: | Alzheimer's/disease Neuroimaging |
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