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Inadequate cytoplasmatic calcium signals in alveolar macrophages after cardiac surgery |
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| Authors: | Katharina Berger Michael Sander Anke Kohlar Christian Meisel Wolfgang Konertz Thomas Volk |
| Institution: | 1. Department of Anesthesiology and Intensive Care Medicine, Charité-Universit?tsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany 2. Department of Immunology, Charité-Universit?tsmedizin Berlin, Campus Charité Mitte, Berlin, Germany 3. Department of Cardiovascular Surgery, Charité-Universit?tsmedizin Berlin, Campus Charité Mitte, Berlin, Germany 4. Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Hospital, Universit?tsklinikum des Saarlandes, Kirrberger Straβe 100, 66424, Homburg, Saarland, Germany |
| Abstract: | Objective and designPatients undergoing cardiac surgery have an elevated risk for pulmonary complications. A dysfunction of alveolar macrophages (AM) might promote postoperative infections. Therefore intracellular calcium Ca2+]i as an important second messenger in cellular signaling was assessed in AM. |
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