复方玄驹胶囊与麒麟丸治疗少弱精症的临床观察

目的 观察复方玄驹胶囊、麒麟丸治疗少弱精症患者的疗效.方法 采用服药前后自身对照及两种药物相互对照的临床研究方法,对100例少弱精症患者随机分为两组.一组口服复方玄驹胶囊（3粒,3次/日）、一组口服麒麟丸（6g,3次/日）,12周为一个疗程.以精子密度和（a＋b）级精子为主要疗效指标,以a级精子、精子活动率为次要疗效指标,评价两种药物的效果.结果 有95例患者完成了临床研究,两组在精子密度、（a＋b）级精子、a级精子和精子活动率,治疗完成后较治疗前均有显著性差异（P＜0.05）.治疗完成后两组在精子密度、（a＋b）级精子、a级精子差异有统计学意义（P＜0.05）,而在精子活动率上无统计学差异（P＞0.05）.结论 两药物对少弱精症患者精液质量的提高均有一定的治疗效果,复方玄驹胶囊对少弱精症的效果较麒麟丸更佳.

Clinical efficacy of fufang xuanju capsule and qilin pills on oligoasthenospermia

Objectives To observe the clinical effects of Fufang Xuanju capsules and Qilin Pills in patients oligoasthenospermia.Methods Using a self-controlled before and after taking one drug and a comparison of two drugs clinical trials,A total of 100 infertile men oligoasthenospermia were equally randomized into two groups.One group was treated with Fufang Xuanju capsules（3,3 times / day）,Another was treated with Qilin pills（6g,3 times/ day） for 12 weeks as a course.We evaluated the efficacy of the drugs with sperm concentration and vitality（a ＋ b） as the primary and the number of grade a sperm and sperm motility as the secondary therapeutic indexes.Results A total of 95 patients accomplished the clinical study.Two groups were significantly different before and after treatment in sperm concentration,vitality （a ＋ b）,the number of grade a sperm and sperm motility （P ＜ 0.05）.The difference was statistically significant in two groups in sperm density,grade（a ＋ b） sperm and the number of grade a sperm（P ＜ 0.05）,whereas no statistically significant difference on sperm motility （P ＞ 0.05）.Conclusions The two drugs both have a therapeutic effect on oligoasthenospermia,But Fufang Xuanju capsules is better than Qilin Pills.