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针灸促进骨折愈合机制的研究进展
引用本文:陈计稳,王华军,郑小飞.针灸促进骨折愈合机制的研究进展[J].中国骨伤,2020,33(1):93-96.
作者姓名:陈计稳  王华军  郑小飞
作者单位:暨南大学第一临床医学院 暨南大学附属第一医院骨关节与运动医学中心, 广东 广州 510630,暨南大学第一临床医学院 暨南大学附属第一医院骨关节与运动医学中心, 广东 广州 510630,暨南大学第一临床医学院 暨南大学附属第一医院骨关节与运动医学中心, 广东 广州 510630
基金项目:中国博士后科学基金资助项目(编号:2015M582480,2017T100660);广东省自然科学基金项目(编号:2016A030313100);国家自然科学基金项目(编号:81601219)
摘    要:针灸对促进骨折愈合有着显著的疗效,具有疏通经络、调和气血、消肿散淤等作用,然而其机制仍然未完全阐明。随着研究的不断深入,近年来发现针灸促进骨折愈合的机制涉及调节细胞生长因子表达水平,激活WNT/β-catenin等信号通路,改善局部的血液循环,影响骨中矿物元素的含量,调节内分泌系统,促进骨细胞的分化与增殖,促进成骨细胞的增生与激活和影响骨细胞凋亡等多方面。针灸促进骨折愈合的机制非常复杂,尚处于动物实验和细胞水平,本文对以上研究进展进行综述总结。

关 键 词:针灸疗法  骨折愈合  综述
收稿时间:2019/2/20 0:00:00

Research progress on mechanism of acupuncture and moxibustion promoting fracture healing
CHEN Ji-wen,WANG Hua-jun and ZHENG Xiao-fei.Research progress on mechanism of acupuncture and moxibustion promoting fracture healing[J].China Journal of Orthopaedics and Traumatology,2020,33(1):93-96.
Authors:CHEN Ji-wen  WANG Hua-jun and ZHENG Xiao-fei
Institution:Bone Joint and Sport Medical Center, the First Clinical College of Jinan University, the First Affiliated Hospital of Jinan University, Guangzhou 510630, Guangdong, China,Bone Joint and Sport Medical Center, the First Clinical College of Jinan University, the First Affiliated Hospital of Jinan University, Guangzhou 510630, Guangdong, China and Bone Joint and Sport Medical Center, the First Clinical College of Jinan University, the First Affiliated Hospital of Jinan University, Guangzhou 510630, Guangdong, China
Abstract:Acupuncture has a significant effect on promoting fracture healing.It can dredge meridians and collaterals,regulate qi and blood,eliminate swelling and remove stasis.However,its mechanism is still not fully elucidated.With the development of research,it has been found in recent years that the mechanism of acupuncture and moxibustion promoting fracture healing involves regulating the expression level of cell growth factor,activating Wnt/β-Catenin and other signal pathways,improving local blood circulation,affecting the content of mineral elements in bone,regulating the endocrine system,promoting the differentiation and proliferation of bone cells,promoting the proliferation and activation of osteoblasts and influencing the apoptosis of bone cells And so on.The mechanism of acupuncture and moxibustion promoting fracture healing is very complex,which is still at the level of animal experiments and cells.
Keywords:Acupuncture-moxibustion  Fracture healing  Review
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