呼吸系统弹性回位压的测定及临床应用

作者采用殖气位（ＲＶ）和功能残气位（ＦＲＣ）两个肺容积位的最大吸气口腔压（ＭＩＰ）之差，等于ＲＶ位的吸附系统弹性回位压（Ｐｒｓ）的原理，测定出ＲＶ位的Ｐｒｓ。并用此法对２０例正常人、９０例慢性阻塞性肺疾病（ＣＯＰＤ）及１５例肺间质纤维化（Ｉｎｔｅｒｓｔｉｔｉａｌ ｌｕｎｇ ｆｉｂｒｏｓｉｓ，ＩＬＦ）患者进行了ＲＶ位Ｐｒｓ的测定，同时对ＲＶ位Ｐｒｓ和残气容积／肺总量（ＲＶ／ＴＬＣ％）进行了相关分析，

Measurement and clinical use of recoil pressure of the respiratory system]

Using the principle that the difference of MIP (maximal inspiratory mouth pressure) between RV (residual volume) and FRC (functional residual capacity) equals Prs (recoil pressure of the respiratory system) at RV, we performed the measurement of Prs at RV in 20 normal subjects, 90 patients with COPD (chronic obstructive pulmonary disease) and 15 patients with ILF (interstitial lung fibrosis). We also performed the correlation analysis of Prs at RV and RV/TLC (total lung capacity) %. The results indicated the Prs values at RV (-2.8 +/- 0.5 kPa) in normal subjects measured in this manner was in accord with the values reported by other authors abroad. The Prs in patients with emphysema decreased and it was highly and negatively correlated with RV/TLC% (r = -0.872), but the Prs in patients with ILF was increased. The results suggest that this method for measurement of Prs is simple, reliable, and clinically useful.