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远端缺血预处理心肌保护效应研究进展
引用本文:辛平,朱伟,魏盟.远端缺血预处理心肌保护效应研究进展[J].中国实用内科杂志,2010(4).
作者姓名:辛平  朱伟  魏盟
作者单位:上海交通大学附属第六人民医院心内科;
基金项目:上海交通大学医学院“博士创新基金”资助(BXJ0932)
摘    要:远端缺血预处理(RIPC)是通过给予一个器官缺血预处理可以增加远处器官对缺血再灌注损伤的耐受性。基础研究和临床试验均证实RIPC是一项安全有效的干预措施,具有降低心肌缺血再灌注损伤的心肌保护效应。本文就近年来RIPC心肌保护效应和临床应用研究新进展做一综述。

关 键 词:缺血预处理  缺血再灌注损伤  

Advance in the cardioprotective effects offered by remote ischemic preconditioning
XIN Ping,ZHU Wei,WEI Meng.Advance in the cardioprotective effects offered by remote ischemic preconditioning[J].Chinese Journal of Practical Internal Medicine,2010(4).
Authors:XIN Ping  ZHU Wei  WEI Meng
Institution:XIN Ping,ZHU Wei,WEI Meng.Department of Cardiology,the Sixth People\'s Hospital,Shanghai Jiaotong University,Shanghai 200233,China
Abstract:Remote ischaemic preconditioning(RIPC)is defined as brief ischemia in one organ could confer resistance to subsequent lethal ischemia insults in remote organ.Accumulating data from either basic research or clinical trials had demonstrated the cardioprotective effect offered by RIPC,which is a safe and effective means of reducing ischemia reperfusion injury.The aim of the review is to summarize the advance in the clinical application of RIPC.
Keywords:ischemic preconditioning  ischemia reperfusion injury  
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