| HPLC法测定肝健胶囊中齐墩果酸的含量 |
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| 引用本文： | 王宏. HPLC法测定肝健胶囊中齐墩果酸的含量[J]. 北方药学, 2010, 7(5): 10-11 |
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| 作者姓名： | 王宏 |
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| 作者单位： | 青海省西宁市三普药业股份有限公司,西宁,810007 |
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| 摘 要： | 目的：建立用HPLC法测定肝健胶囊中齐墩果酸含量的方法.方法：色谱柱为kromasil.C18柱（250mmx4.6mm 5um）,流动相为乙腈-水（9：1）,检测波长210nm,柱温30℃,流速为1.0ml/min.结果：齐墩果酸在40.16～200.8ug/ml范围内与峰面积呈良好线性关系,回归方程：Y=5741.4X＋3751.6.r=0.9998,平均回收率96.49%（n=6）,RSD=0.68%.结论：该方法重复性好,结果准确,可用于肝健胶囊质量控制.
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| 关 键 词： | HPLC 肝健胶囊 齐墩果酸 |
Determination the Content of Oleanolic acid in Ganjian capsule by HPLC |
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| Wang Hong. Determination the Content of Oleanolic acid in Ganjian capsule by HPLC[J]. BEIFANG YAOXUE, 2010, 7(5): 10-11 |
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| Authors: | Wang Hong |
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| Affiliation: | Wang Hong (S＆P Pharmaceutical Co. Ltd. QinghaiXining 810007 China) |
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| Abstract: | Objective To establish the HPLC method for determining the content of Oleanolic acid in Ganjian Capsule. Method The column was Kromasil C-18 （250mmx4.6mm 5um）The mobile phase was acetonitrile-water （9：1）the detection wavelength was 210nm the column temperature was 30℃ with the flow rate Of 1.0ml/min. Results The linear range was 40.16 to 200.Sug/ml for paeonol （r= 0.9998 ） The recovery was 96.49% and with RSD=0.68% Conclusion The method is accurate and highly reproducible .It can be a method for quality control of Ganjian Capsule. |
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| Keywords: | HPLC Ganjian Capsule Oleanolie acid |
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