Multifocal electroretinogram findings after intravitreal bevacizumab injection in choroidal neovascularization of age-related macular degeneration期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Multifocal electroretinogram findings after intravitreal bevacizumab injection in choroidal neovascularization of age-related macular degeneration

Authors:	Park Joo Youn Kim Seung Hoon Park Tae Kwann Ohn Young-Hoon

Institution:	Department of Ophthalmology, Soonchunhyang University College of Medicine, Bucheon, Korea.

Abstract:	Purpose To evaluate the changes in multifocal electroretinogram (mfERG) and optical coherence tomography (OCT) after intravitreal bevacizumab injection in the treatment of age-related macular degeneration (AMD). Methods Twenty-one eyes with choroidal neovascularization secondary to AMD were studied before and after intravitreal bevacizumab injection for best corrected visual acuity (BCVA), OCT, and mfERG. Results The BCVA improved, while central macular thickness and total macular volume in OCT decreased after intravitreal bevacizumab injection (p = 0.03, 0.01, and 0.01, respectively). In mfERG, the amplitude of P1, and implicit time of P1 and N1 indicated a statistically significant improvement of retinal response after intravitreal bevacizumab injection. Conclusions There is a potential role for mfERG in evaluating the effect on retinal function of intravitreal bevacizumab injection.

Keywords:	Age-related macular degeneration Bevacizumab Choroidal neovascularization Multifocal electroretinogram Optical coherence tomography
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