| 高渗与低渗造影剂对原有肾损害大鼠肾毒性的研究 |
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| 引用本文： | 段绍斌,罗季安,伍汉文,刘瑞洪.高渗与低渗造影剂对原有肾损害大鼠肾毒性的研究[J].中南大学学报(医学版),1996(3). |
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| 作者姓名： | 段绍斌 罗季安 伍汉文 刘瑞洪 |
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| 作者单位： | Department of Medicine，The Second Affiliated Hospital，Hunan Medical University |
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| 摘 要： | 研究高、低渗造形剂（泛影葡胺、欧乃派克）对甘油肾损害大鼠肾毒性及氨氯地平的保护作用。结果表明：高渗造影剂组血清尿素氨和血清肌酐、肾组织磷脂酶Ａ２、脂质过氧化物含量，肾小管损害积分均明显高于低渗造影剂组及甘油对照组（Ｐ＜０．０５）。氨氯地平预防组肾损害明显轻于高渗适影剂组。提示低渗造影剂肾毒性较小，氨氯地平对泛影葡胺肾毒性有保护作用。
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| 关 键 词： | 泛影葡胺 欧乃派克 氨氯地平 疾病模型，动物 大鼠 |
EXPERIMENTAL STUDY OF HIGH AND LOW OSMOLAR CONTRAST MEDIA INDUCED NEPHROTOXICITY ON RAT WITH DAMAGED KIDNEY |
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| Duan Shaobin,LuoJi-an, Wu Hanwen.EXPERIMENTAL STUDY OF HIGH AND LOW OSMOLAR CONTRAST MEDIA INDUCED NEPHROTOXICITY ON RAT WITH DAMAGED KIDNEY[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1996(3). |
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| Authors: | Duan Shaobin LuoJi-an Wu Hanwen |
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| Abstract: | |
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| Keywords: | contrast media diatrizoate meglunine iohexol renal failure amlodipinedisease model animal:rats |
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