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Effect of Nitrous Oxide on Spike Activity During Epilepsy Surgery
Authors:Y. Sato  K. Sato  H. Shamoto  M. Kato  T. Yoshimoto
Affiliation:(1) Department of Neuroanesthesia, Kohnan Hospital, Japan, JP;(2) Department of Neurosurgery, Kohnan Hospital, Japan, JP;(3) Department of Anesthesiology, Tohoku University, School of Medicine, Japan, JP;(4) Department of Neurosurgery, Tohoku University, School of Medicine, Japan, JP
Abstract:Summary. There are controversies over the effect of nitous oxide on the electrocorticograms in patients with epilepsy. To clarify the effect of nitrous oxide on electrocorticograms, spike activities were compared with and without nitrous oxide under neuroleptoanesthesia in 10 patients with intractable epilepsy during surgery. Spikes decreased with nitous oxide significantly (P<0.01) and disappeared in 3 cases. We conclude that discontinuation of nitrous oxide should be taken into consideration during electrocorticographic monitoring in epilepsy surgery.
Keywords:: Nitrous oxide   epilepsy   electrocorticogram.
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