Central nervous system germinoma: retrospective study of six cases] |
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| Authors: | H Sifat K Haddadi E el Ghazi H Errihani M Kamouni H Mansouri K Hassouni H Bakkali L Kanouni M Gaye T Kebdani N Benjaafar B K el Gueddar |
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| Institution: | Service de radiothérapie, Institut national d'oncologie, BP 6213 RI-Rabat, Maroc. |
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| Abstract: | PURPOSE: Retrospective analysis of six patients with intracranial germinoma treated in INO and a literature review. MATERIALS AND METHODS: Six patients were treated from 1993 to 1998, for histologically verified primary intracranial germinoma. Median age was 18 years (range: 14-26 years). All patients received chemo-radiotherapy (4FP + radiotherapy from 30 to 50 Gy). RESULTS: 4 tumours were in complete remission. Two patients have kept non-evolutive residual cyst. Five patients are alive with non-evolutive disease after 15-40 months of follow-up (average: 27 months). One patient was lost to follow-up, 14 months after treatment, without disease. CONCLUSION: The treatment of intracranial germinoma is currently first line chemotherapy followed by low-dose and limited irradiation. |
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